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Tran, Ngoc Bich. Viroses immunodépressives des palmipèdes : Approches moléculaires appliquées au diagnostic et l'épidémiologie du Goose Hemorrhagic Polyomavirus (GHPV) et du Duck Enteritis Virus (DEV)

Tran, Ngoc Bich (2008). Viroses immunodépressives des palmipèdes : Approches moléculaires appliquées au diagnostic et l'épidémiologie du Goose Hemorrhagic Polyomavirus (GHPV) et du Duck Enteritis Virus (DEV).

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Résumé en francais

Duck Plague (DP) and Nephritis Hemorrhagic Enteritis of Geese (NHEG) are immunodepressive viral infections of waterfowl, which lead to immunodepressive syndromes in subjects affected, are also dominant pathological able to induce the losses most important. Having designed to assess the exact prevalence and epidemiological situation of two diseases in France, we used modern techniques such as PCR (classical and quantitative), sequencing... in our study. The results confirm that the existence of healthy carriers of Goose hemorrhagic polyomavirus (GHPV) in the population of geese engraved with the prevalence of infection is very varied depending on the lots (53 to 100%) and individuals (5,5 to 82%) by PCR used (classical or quantitative) and also by itself within infected lots. For the duck plague (DP), our studies have totally confirmed the presence of the plague duck among domestic and wild waterfowl in France, the rate of infection DEV in the samples analyzed is fairly high, averaging 32%; the appearance of plague duck takes a seasonal aspect (spring). On the other hand, the role of holder of DEV in wild waterfowl (mallards) and vertical transmission of DEV from reproducer duck to their duckling is clearly demonstrated. In addition, it has detected the pathogenic genes gH and TK in the samples with positive DEV and the sequencing and comparison with other authors. The result showed that ours are perfectly identical (99% to 100%) to others.

Sous la direction du :
Directeur de thèse
Bodin, Guy
Guerin, Jean-Luc
Ecole doctorale:Biologie, santé, biotechnologies (BSB)
laboratoire/Unité de recherche :Interaction Hôtes Agent Pathogène (IHAP), UMR 1225 INRA-ENVT
Mots-clés libres :virose immunodépressive - palmipèdes - PCR, séquençage - épidémiologie
Sujets :Sciences du vivant
Déposé le :24 Feb 2009 16:40